| Description | Correspondence with Professor J.H. Gaddum, F.R.S., Pharmacological Laboratory, University of Edinburgh, regarding implications of a paper by Gaddum and Picarelli, including 'the presence and localisation of M and D receptors', 'the rather feeble antagonosm of morphine and atropine to nicotine' and the development of tolerances towards morphine, April 1957: Gaddum states 'I have not seen tolerance developed towards morphine but this is mainly because I have not looked for it. I have quite recently been rather disturbed by Paton who says that when once one has produced a given effect by morphine tolerance is so marked that the effect cannot be increased by increasing the dose.' Also, letter from Kosterlitz thanking Gaddum for sending him 'the substance P which arrived safely today', 17 January 1957, with a typed note on the development and use of the substance.
Letter from Kosterlitz to Professor Antoine Giroud, Faculte de Medicine, Paris, enclosing reprints of Aberdeen papers on changes in the liver during pregnancy and looking forward to receiving copies of Giroud's reprints, 12 September 1957.
Correspondence with Glaxo Laboratories Ltd, Medical Department, Greenford, regarding the supply of Cortelan Injection, May 1959 and phenadoxine hydrochloride, October 1961.
Correspondence with Mr A.F. Green, Wellcome Research Laboratories, Beckenham, Kent, regarding mutual current research interests in the effects of bretylium on the peristaltic reflex, July 1959 - February 1960. The lengthy correspondence discusses results and analysis of experiments, forthcoming presentations to the Physiological Society, and publication of papers on the topic. |